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    Référence: 20210512
    Date de publication: 24 mars 2022

    Promoteur – Intermédiaire Financier

    DIADEM SRL

    Lieu

    Description

    Quasi-equity financing to Diadem, an Italian biotechnology company developing prognostic testing for early detection of Alzheimer's disease.

    Additionality and Impact

    The project concerns an operation under the European Guarantee Fund. The purpose of the loan is to provide direct, equity-type financing under EIB's Venture Debt Instrument to support Research, Development and Innovation ("RDI") activities of the innovative company 'Diadem', an SME based in Italy, which has been impacted by the COVID-19 pandemic. The financing of this project addresses the failure in financial markets for RDI, arising from limited access to commensurate financing as a result of factors such as information asymmetries, misalignment of incentives, etc. The Promoter is a dedicated medical technology company developing innovative solutions for the early prediction and diagnosis of Alzheimer's disease, with the aim of potentially enabling early interventions to slow disease progression. The project targets an unmet need with high socio-economic impact. By creating knowledge externalities, the project will provide significant socio-economic benefits, will strengthen Italy and Europe's leading position in medical technologies, and it will help to retain skilled staff engaged in the Company's RDI activities. 

    EIB's financing would be complementary to European venture capital ("VC") investors and would provide a signalling effect to crowd-in other capital providers, which are necessary for the completion of the clinical development stage and the launch of commercial operations. Hence, thanks to EIB's involvement, this project will not be significantly delayed due to the crisis.

    Objectifs

    The proposed transaction will support research and development (R&D) investments to address a high-unmet medical need in the fields of prediction and diagnosis of Alzheimer's Disease (AD), a disease that has a high economic and social burden globally. Diadem's technology is offering the unique possibility to detect AD at an early stage or even predict AD in asymptomatic patients, which may provide the great opportunity to start preventive therapies with disease-modifying treatments (DMTs) and/or non-pharmaceutical interventions that may change the progression of the disease. The project supports ongoing R&D activities conducted by the Promoter and its network of partners, which encompasses universities, research institutes and other private companies (suppliers, etc.). It represents a rational allocation of resources. Furthermore, this project sustains the Promoter's long-term growth through the development of innovative diagnostic tools.

    Secteur(s)

    • Services - Activités spécialisées, scientifiques et techniques

    Montant BEI envisagé (montant approximatif)

    EUR 8 million

    Coût total (montant approximatif)

    EUR 20 million

    Aspects environnementaux

    The proposed transaction will support research and development (R&D) investments that are required in order to advance the clinical development of an innovative product in indications that address a high unmet medical need. By co-investing in the project, the Bank contributes to improving healthcare, whilst also fostering the generation of European scientific knowledge and acumen, preserving and cultivating highly skilled employment opportunities. Developing orally applied receptor modulators for hematologic malignancies, i.e. cancers that affect the blood, bone marrow, and lymph nodes, commonly known as leukaemia.

    Passation des marchés

    The Promoter is a private company not operating in the utilities sector and not having the status of a contracting authority; thus, the project is not covered by the EU Directives on procurement. However, the Promoter's procurement procedures are expected to be in line with EIB guidelines for private sector projects. The Bank's services will verify details during the project due diligence.

    Statut

    Signé - 24/02/2022

    Clause de non-responsabilité

    Avant d’être approuvés par le Conseil d’administration et avant la signature des prêts correspondants, les projets font l’objet d’une instruction et de négociations. Par conséquent, les informations et données fournies sur cette page sont indicatives.
    Elles sont fournies à des fins de transparence uniquement et ne peuvent être considérées comme représentant la politique officielle de la BEI (voir également les notes explicatives).

    Mots-clés correspondants

    Italie Services